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DRUGS OF ABUSE TESTS
Drugs of Abuse ("DOA") tests are rapid a nd qualitative
assays for the detection of opiate, tetrahydrocannabinol ("THC"),
methamphetamine, amphetamine and/or their metabolites present in
human urine at the cut-off concentration of the drug specified.
Morphine, codeine and semi synthetic derivatives of morphine belong
to the class of drugs called opiate. Morphine is the prototype compound
of opiate and is excreted into the urine as morphine-3-glucoronide,
unchanged morphine and other minor metabolites. Heroin is metabolised
to morphine and codeine. THC is a primary active ingredient in cannabinoid
("marijuana"). Methamphetamine and amphetamine are potent
sympathomimetic agents with therapeutic applications. Methamphetamine
is excreted in the urine primarily as amphetamine as well as oxidized
and deaminated derivatives. Amphetamine is excreted in the urine
in unchanged from and also as hydroxylated and deaminated derivatives.
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